Vitamin B6 may help keep Covid cytokine storms at bay: Study

Vitamin B6 may help keep Covid cytokine storms at bay: Study
HIROSHIMA: A recent study led by nutritional scientist Thanutchaporn Kumrungsee may be the first step to demonstrate the potential of vitamin B6 to reduce the likelihood of patients becoming seriously ill from the coronavirus.
The study paper published in the journal Frontiers in Nutrition found that vitamin B6 can help calm cytokine storms and unclog blood clots linked to Covid-19's lethality. But research is lacking.
Studies so far have explored the benefits of vitamins D and C and minerals such as zinc and magnesium in enhancing the immune response against Covid-19. But research on vitamin B6 was largely lacking.
"In addition to washing your hands, food and nutrition are among the first lines of defense against Covid-19 virus infection. Food is our first medicine and kitchen is our first pharmacy," said Kumrungsee, associate professor at Hiroshima University's Graduate School of Integrated. . Sciences for Life, said.
"Recently, many scientists have published articles on the role of diets and nutrients in protecting against Covid-19. However, few scientists are paying attention to the important role of vitamin B6," she added.
In their paper, she and her fellow researchers pointed to growing evidence showing that vitamin B6 has a protective effect against chronic diseases such as cardiovascular disease and diabetes by suppressing inflammation, inflammasomes, oxidative stress and carbonyl stress.
Coronaviruses and influenza are among the viruses that can cause fatal lung injury and death as a result of acute respiratory distress syndrome worldwide. Viral infections evoke a 'cytokine storm', which leads to pulmonary capillary endothelial inflammation, neutrophil infiltration and increased oxidative stress . " said.
Kumrungsee explained that thrombosis (blood clotting) and cytokine storm (hyperinflammation) may be closely related to the severity of Covid-19. Cytokine storms happen when the immune system goes into dangerously overdrive and even starts attacking the healthy cells. Meanwhile, blood clots linked to Covid-19 can block capillaries and damage vital organs such as the heart, lungs, liver and kidneys.
Vitamin B6 is a known nutrient against thrombosis and inflammation. Deficiency of this vitamin is also associated with lower immune function and higher susceptibility to viral infections.
Vitamin B6 has a close relationship with the immune system. Its levels are always decreasing in people with chronic inflammation such as obesity, diabetes and heart disease. We can see from the news that obese and diabetics are at high risk for Covid-19., & # 39; Kumrungsee said.
"So our attempt in this article is to shed light on the potential involvement of vitamin B6 in reducing the severity of Covid-19."
The associate professor said she is looking forward to clinical trials that would test their hypothesis.
"It is very important to investigate whether vitamin B6 protects against new types of viral infections and pneumonia that will occur in the future. Currently, there is little information about the protective role of nutrients against pneumonia and lung diseases," she says. said.
"After Covid-19, we should develop the field of nutrition for lung diseases such as pneumonia and lung cancer."

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